Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11001007 | 0.85 | LMNA (0.52) | PTGS1PTGS2LMNAF13A1TSHR | |
| Maleic Anhydride SCHEMBL1042382 | 0.85 | TDP1 (0.48) | TSHRTDP1 | |
| Sebacic Acid SCHEMBL8856373 | 0.83 | TSHR (0.55) | PTGS1PTGS2LMNAF13A1TSHR | |
| Sebacic Acid SCHEMBL3454140 | 0.83 | TSHR (0.55) | PTGS1PTGS2LMNAF13A1TSHR | |
| Sebacic Acid SCHEMBL27554744 | 0.82 | GPR84 (0.52) | PTGS1PTGS2LMNAF13A1TSHR | |
| Maleic Anhydride SCHEMBL735380 | 0.82 | MAPT (0.53) | PTGS1PTGS2LMNATSHRTDP1 | |
| Maleic Anhydride SCHEMBL28887980 | 0.81 | TDP1 (0.43) | TDP1 | |
| Adipic Acid SCHEMBL9696395 | 0.81 | LMNA (0.48) | PTGS1PTGS2LMNAF13A1TSHR | |
| Adipic Acid SCHEMBL10936251 | 0.81 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL346488 | 0.81 | LMNA (0.58) | LMNATSHRNFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129533-A1 | COMPOSITIONS FOR PREPARING MEMBRANES FROM POLYMER SOLUTIONS | THE LUBRIZOL CORPORATION (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-117355290-A | Hair coloring composition for reducing color loss | 路博润先进材料公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230416653-A1 | ANTIMICROBIAL CLEANING COMPOSITIONS CONTAINING POLYURETHANE SALTED WITH BIS-BIGUANIDE FREE BASE | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-12-28 | — | — | US | disclosed |
| EP-4247928-A1 | ANTIMICROBIAL CLEANING COMPOSITIONS CONTAINING POLYURETHANE SALTED WITH BIS-BIGUANIDE FREE BASE | Lubrizol Advanced Materials, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116425942-A | Aqueous polyurethane dispersion and composition containing same | 长兴化学工业(中国)有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116438287-A | Antimicrobial cleansing compositions containing polyurethanes salified with bis-biguanide free base | 路博润先进材料公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20220403162-A1 | POLYURETHANE COMPOSITIONS SALTED WITH BISBIGUANIDE | LUBRIZOL ADVANCED MATERIALS, INC | 2022-12-22 | — | — | US | disclosed |
| EP-4061899-A1 | POLYURETHANE COMPOSITIONS SALTED WITH BISBIGUANIDE | Lubrizol Advanced Materials, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| CN-114846096-A | Polyurethane compositions salified with bis-biguanides | 路博润先进材料公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220226784-A1 | Hollow Fiber Membrane | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2022-07-21 | — | — | US | disclosed |
| WO-2006082241-A2 | A PROCESS FOR PRODUCING A WATER-ABSORBING MATERIAL HAVING A COATING OF ELASTIC FILMFORMING POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006083585-A2 | ABSORBENT STRUCTURE WITH IMPROVED WATER-ABSORBING MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060177647-A1 | Absorbent structure with improved water-swellable material | PROCTER & GAMBLE COMPANY, THE | 2006-08-10 | — | — | US | disclosed |
| US-20060178071-A1 | Absorbent structure with improved water-absorbing material | THE PROCTER & GAMBLE COMPANY | 2006-08-10 | — | — | US | disclosed |
| WO-2006083583-A2 | ABSORBENT STRUCTURE WITH IMPROVED WATER-SWELLABLE MATERIAL | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006079098-A1 | AQUEOUS DISPERSIONS OF NANOPARTICLE/POLYURETHANE COMPOSITES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006023790-A1 | CURABLE THIOCARBONATE COMPOUNDS AND COMPOSITIONS | NOVEON, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006020116-A1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| WO-2006020281-A1 | POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20050009999-A1 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-01-13 | — | — | US | disclosed |