Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626066 | 0.90 | POLB (0.41) | TSHRPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL11625289 | 0.87 | KDM4E (0.43) | TSHRPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL11624146 | 0.86 | TSHR (0.40) | KMT2ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL11460905 | 0.83 | GAA (0.46) | KMT2ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL11628340 | 0.83 | MAPT (0.39) | TSHRPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL11627896 | 0.83 | TSHR (0.40) | KMT2ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL11381545 | 0.81 | POLB (0.39) | KMT2ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL11007676 | 0.80 | ALDH1A1 (0.40) | KMT2ATSHRPOLBLMNAALDH1A1 | |
| SCHEMBL11381103 | 0.79 | KCNA5 (0.40) | TSHRPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL7750623 | 0.77 | SMN1; SMN2 (0.39) | KMT2ATSHRLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515791-A | Substituted phenyl-1,2,4-triazolo[2,3-b]pyridazin-3(2H)ones as anti-asthma agents | AMERICAN CYANAMID COMPANY (US) | 1985-05-07 | — | — | US | disclosed |