Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624146 | 0.82 | TSHR (0.40) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11381545 | 0.81 | POLB (0.39) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11625289 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4ETSHRPOLBLMNA | |
| SCHEMBL11003097 | 0.80 | KMT2A (0.39) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL3919339 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11628340 | 0.79 | MAPT (0.39) | ALDH1A1KDM4EHPGDTSHRPOLB | |
| SCHEMBL11460905 | 0.79 | GAA (0.46) | ALDH1A1KDM4EKMT2ATSHRPOLB | |
| SCHEMBL11381103 | 0.77 | KCNA5 (0.40) | ALDH1A1KDM4EHPGDTSHRPOLB | |
| SCHEMBL11626066 | 0.76 | POLB (0.41) | ALDH1A1KDM4ETSHRPOLBLMNA | |
| SCHEMBL11627896 | 0.75 | TSHR (0.40) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515791-A | Substituted phenyl-1,2,4-triazolo[2,3-b]pyridazin-3(2H)ones as anti-asthma agents | AMERICAN CYANAMID COMPANY (US) | 1985-05-07 | — | — | US | disclosed |