SCHEMBL11003296

SCHEMBL11003296

CC(C)c1ccc(O)c(CN(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
GAA P10253 2/20 0.57
KDM4E B2RXH2 2/20 0.57
MAPT P10636 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
MEN1 O00255 1/20 0.57
POLB P06746 1/20 0.57
THRB P10828 1/20 0.57
G6PD P11413 1/20 0.57
PABPC1 P11940 1/20 0.57
KMT2A Q03164 1/20 0.57
HKDC1 Q2TB90 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
HTT P42858 3/20 0.50
ALOX12 P18054 2/20 0.50
HIF1A Q16665 1/20 0.50
RNASEH1 O60930 1/20 0.47
TRPA1 O75762 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11002601 0.84 GAA (0.57) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL26137530 0.82 CYP1A2 (0.47) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL26266000 0.82 LMNA (0.50) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL50460 0.82 ALDH1A1 (0.55) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL24116084 0.81 CYP1A2 (0.47) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL20982391 0.81 CYP1A2 (0.47) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL13091293 0.81 CYP1A2 (0.46) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL10215349 0.80 ADRB2 (0.54) ALDH1A1GAATDP1CYP1A2CYP2D6
SCHEMBL11282907 0.80 CYP2D6 (0.72) ALDH1A1GAAKDM4EMAPTTDP1
SCHEMBL5167176 0.80 RNASEH1 (0.55) ALDH1A1GAAKDM4EMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4537920-A 4H-1-benzopyrans and lubricant compositions containing same ETHYL CORPORATION (US) 1985-08-27 US disclosed