Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006418 | 0.85 | HSD17B1 (0.35) | BCHE | |
| SCHEMBL11006279 | 0.81 | NPC1 (0.38) | ALDH1A1SMN1; SMN2GSK3BKDM1ALMNA | |
| SCHEMBL11010863 | 0.78 | GSK3B (0.32) | GSK3B | |
| SCHEMBL8559832 | 0.78 | GSK3B (0.34) | GSK3B | |
| SCHEMBL11005893 | 0.75 | GSK3B (0.34) | ALDH1A1GSK3BLMNAL3MBTL1BCHE | |
| SCHEMBL3866344 | 0.74 | GSK3B (0.34) | GSK3BDRD2BCHE | |
| SCHEMBL9569380 | 0.73 | GSK3B (0.34) | GSK3BLMNATDP1MEN1KMT2A | |
| SCHEMBL30085699 | 0.72 | HRH3 (0.39) | ALDH1A1KDM1ALMNAMEN1KMT2A | |
| SCHEMBL9569405 | 0.71 | EGFR (0.43) | MAOAKDM1AL3MBTL1MAPTMAPK1 | |
| SCHEMBL11007770 | 0.71 | BCHE (0.33) | GSK3BLMNAL3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |