Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011070 | 0.86 | NPC1 (0.34) | NPC1RAB9APOLBKDM1ACYP1A2 | |
| SCHEMBL11004064 | 0.81 | MAOA (0.38) | KDM1ANOX1KMT2AMAPK1LMNA | |
| SCHEMBL31731877 | 0.74 | ALDH1A1 (0.35) | NPC1RAB9APOLBCYP1A2HTT | |
| SCHEMBL31732573 | 0.72 | ALDH1A1 (0.34) | NPC1RAB9APOLBNPSR1ALDH1A1 | |
| SCHEMBL31732410 | 0.72 | ALDH1A1 (0.36) | CYP1A2NPSR1HTR1AALDH1A1 | |
| SCHEMBL11006418 | 0.71 | HSD17B1 (0.35) | CYP3A4 | |
| SCHEMBL31732417 | 0.70 | MEN1 (0.36) | CYP1A2CYP2D6KMT2AMEN1ALDH1A1 | |
| SCHEMBL7332375 | 0.68 | HSD17B10 (0.34) | POLBKDM1ACYP1A2CYP2D6HTT | |
| SCHEMBL10465122 | 0.68 | ALDH1A1 (0.34) | HTTKDM4EKMT2ANPSR1LMNA | |
| SCHEMBL10559808 | 0.68 | SNCA (0.40) | NPC1RAB9APOLBKDM1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |