Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569385 | 0.82 | MEN1 (0.44) | POLBMEN1KMT2ABCHECHRM2 | |
| SCHEMBL9569380 | 0.80 | GSK3B (0.34) | MEN1KMT2ABCHE | |
| SCHEMBL30085710 | 0.75 | POLB (0.39) | POLBMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL9569356 | 0.72 | CACNA1C (0.39) | MAPK1BCHEMAPTTP53KDM4E | |
| SCHEMBL30085699 | 0.72 | HRH3 (0.39) | POLBMEN1KMT2ATP53KDM1A | |
| SCHEMBL9569373 | 0.72 | GSK3B (0.36) | MEN1KMT2ABCHEMAPTTP53 | |
| SCHEMBL9569336 | 0.72 | BACE1 (0.36) | MEN1KMT2ABCHEMAPTTP53 | |
| SCHEMBL11004064 | 0.71 | MAOA (0.38) | MAPK1MEN1KMT2ABCHECHRM3 | |
| SCHEMBL9271818 | 0.69 | PRNP (0.31) | MEN1KMT2ABCHE | |
| SCHEMBL30085745 | 0.68 | BRD4 (0.41) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |