Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704757 | 0.84 | KMT2A (0.73) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11706540 | 0.82 | KMT2A (0.76) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31014170 | 0.82 | LMNA (0.56) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6151748 | 0.80 | LMNA (0.57) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6151749 | 0.80 | PRMT1 (0.59) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3066281 | 0.80 | LMNA (0.57) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20202315 | 0.79 | ALDH1A1 (0.66) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5020960 | 0.79 | ALDH1A1 (0.82) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL633906 | 0.79 | ALDH1A1 (0.82) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1279062 | 0.79 | ALDH1A1 (0.82) | LMNAHTTMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525450-A | Silver halide color photographic light sensitive material containing a coupler containing at least one of a sulfamoylphenylenesulfonyl, sulfamoylaminophenylenesulfonyl, or sulfoamidophenylenesulfonyl group | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |