SCHEMBL31014170

SCHEMBL31014170

CCCCCNS(=O)(=O)c1cccc(Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
HTT P42858 2/20 0.56
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 3/20 0.56
FBP1 P09467 5/20 0.55
KMT2A Q03164 3/20 0.55
TSHR P16473 3/20 0.55
MEN1 O00255 2/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C19 P33261 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.53
KDM4E B2RXH2 1/20 0.53
PKM P14618 1/20 0.53
PDK1 Q15118 1/20 0.51
PDK2 Q15119 1/20 0.51
PDK3 Q15120 1/20 0.51
PDK4 Q16654 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11706540 0.84 KMT2A (0.76) LMNAHTTMAPK1ALDH1A1FBP1
SCHEMBL196573 0.84 FABP4 (0.66) LMNAHTTMAPK1ALDH1A1KMT2A
SCHEMBL196436 0.84 FABP4 (0.66) LMNAHTTMAPK1ALDH1A1KMT2A
SCHEMBL8377902 0.83 PGR (0.56) LMNAFBP1TDP1PKMPGR
SCHEMBL4070938 0.83 PRMT1 (0.61) LMNAHTTMAPK1ALDH1A1KMT2A
SCHEMBL1465414 0.83 LMNA (0.55) LMNAHTTMAPK1ALDH1A1FBP1
SCHEMBL5505553 0.83 FBP1 (0.59) LMNAALDH1A1FBP1TSHRCYP2C19
SCHEMBL11704757 0.83 KMT2A (0.73) LMNAHTTMAPK1ALDH1A1FBP1
SCHEMBL11004367 0.82 LMNA (0.54) LMNAHTTMAPK1ALDH1A1KMT2A
SCHEMBL13314764 0.82 TSHR (0.61) LMNAHTTMAPK1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439980-B Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2025-04-08 CN disclosed
CN-118439980-A Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2024-08-06 CN disclosed