Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750365 | 0.79 | TRPA1 (0.43) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11003959 | 0.79 | TAS1R3 (0.38) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL8750414 | 0.78 | TRPA1 (0.42) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL385533 | 0.78 | — | — | |
| SCHEMBL11002884 | 0.76 | ALDH1A1 (0.36) | SLC6A2ALDH1A1NPBWR1SMN1; SMN2MCHR1 | |
| SCHEMBL6394395 | 0.76 | ESR1 (0.48) | LMNACHRM1SLC6A2ADRA1AHTR2B | |
| SCHEMBL11786210 | 0.76 | TRPA1 (0.45) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL9073224 | 0.76 | TRPA1 (0.41) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11004431 | 0.74 | ALDH1A1 (0.34) | ALDH1A1NPBWR1SMN1; SMN2MCHR1TAS1R3 | |
| SCHEMBL4671825 | 0.74 | CHRNA7 (0.37) | LMNATDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539151-A | Benzothiazepine derivatives and their method of preparation | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4539150-A | HYPOTENSIVE AGENTS, SULFIDING, CYCLIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-03 | — | — | US | disclosed |