⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004516 | 0.78 | TRPA1 (0.38) | — | |
| SCHEMBL6394395 | 0.72 | ESR1 (0.48) | — | |
| SCHEMBL9276569 | 0.70 | TRPA1 (0.31) | — | |
| SCHEMBL11004514 | 0.69 | ADRA2A (0.40) | — | |
| SCHEMBL11240906 | 0.69 | GABRA1 (0.37) | — | |
| SCHEMBL4617166 | 0.69 | CYP2D6 (0.37) | — | |
| SCHEMBL4972071 | 0.68 | LMNA (0.39) | — | |
| SCHEMBL10436723 | 0.68 | CYP3A4 (0.36) | — | |
| SCHEMBL27868795 | 0.65 | CHRNA7 (0.37) | — | |
| SCHEMBL4671825 | 0.65 | CHRNA7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770436-B1 | RADIATION-ACTIVATED CATALYSTS (RACS), AUTOCATALYTIC REACTIONS, AND PROTECTIVE GROUPS ARE EMPLOYED TO ACHIEVE A HIGHLY SENSITIVE, HIGH RESOLUTION, RADIATION DIRECTED COMBINATORIAL SYNTHESIS OF PATTERN ARRAYS OF DIVERSE POLYMERS | AFFYMETRIX, INC. | 2004-08-03 | — | — | US | claimed |
| US-6083697-A | Chemical amplification for the synthesis of patterned arrays | AFFYMETRIX, INC. (US) | 2000-07-04 | — | — | US | claimed |
| US-4855486-A | Blocked, marked amino acids | KALBAG SURESH M (US) | 1989-08-08 | — | — | US | claimed |
| US-4755558-A | Using internal marker | BECKMAN INSTRUMENTS, INC. (US) | 1988-07-05 | — | — | US | claimed |
| CN-118324762-A | Compounds and compositions for treating CNS disorders | 布鲁奥科制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240173216-A1 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | YALE UNIVERSITY | 2024-05-30 | — | — | US | disclosed |
| US-20240158476-A1 | MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2024-05-16 | — | — | US | disclosed |
| EP-4331618-A2 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | Yale University (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11918695-B2 | Topical formulation of hyperbranched polymer-coated particles | YALE UNIVERSITY (US) | 2024-03-05 | — | — | US | disclosed |
| EP-3294275-B1 | TOPICAL FORMULATION OF HYPERBRANCHED POLYMER-COATED PARTICLES | UNIV YALE (US) | 2024-02-21 | — | — | EP | disclosed |
| US-11897775-B2 | Mesoporous nitric oxide-releasing silica particles, methods of making, and uses thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-02-13 | — | — | US | disclosed |
| US-11896686-B2 | Hyperbranched polyglycerol-coated particles and methods of making and using thereof | YALE UNIVERSITY (US) | 2024-02-13 | — | — | US | disclosed |
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | disclosed |
| US-5783577-A | COMBINATORIAL LIBRARY FOR DRUG SCREENING | TREGA BIOSCIENCES, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| WO-1998020967-A1 | CHEMICAL AMPLIFICATION FOR THE SYNTHESIS OF PATTERNED ARRAYS | AFFYMETRIX, INC. (US) | 1998-05-22 | — | — | WO | disclosed |
| WO-1998010778-A1 | INHIBITION OF APOPTOSIS USING INTERLEUKIN-1β-CONVERTING ENZYME (ICE)/CED-3 FAMILY INHIBITORS | IDUN PHARMACEUTICALS, INC. (US) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997046514-A1 | PROCESS FOR THE PREPARATION OF HYDRAZINE DERIVATIVES USEFUL AS INTERMEDIATES FOR THE PREPARATION OF PEPTIDE ANALOGUES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997010221-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-03-20 | — | — | WO | disclosed |
| US-4855486-A | Blocked, marked amino acids | KALBAG SURESH M (US) | 1989-08-08 | — | — | US | disclosed |
| US-4755558-A | Using internal marker | BECKMAN INSTRUMENTS, INC. (US) | 1988-07-05 | — | — | US | disclosed |