SCHEMBL11005358

SCHEMBL11005358

CC(C)(C(=O)C(Br)Oc1ccccc1Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 4/20 0.40
HPGD P15428 4/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
SLC6A9 P48067 1/20 0.37
POLB P06746 1/20 0.36
CXCL8 P10145 1/20 0.36
CNR1 P21554 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
GAA P10253 1/20 0.34
GHSR Q92847 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11005546 0.87 PPARA (0.48) ALDH1A1MAPTKMT2AHPGDLMNA
SCHEMBL11004556 0.81 CNR1 (0.42) ALDH1A1MAPTKMT2ACNR1PPARG
SCHEMBL11007296 0.80 KMT2A (0.46) ALDH1A1MAPTKMT2AHPGDLMNA
SCHEMBL11001230 0.80 PPARA (0.43) MAPTKMT2AMEN1PPARGPPARA
SCHEMBL11003980 0.78 OGG1 (0.44) ALDH1A1MAPTKMT2ALMNAPOLB
SCHEMBL11002653 0.77 PPARG (0.43) MAPTKMT2AMEN1PPARGPPARA
SCHEMBL11006062 0.75 PPARG (0.42) MAPTKMT2ALMNAMEN1SLC6A9
SCHEMBL11002962 0.74 PPARG (0.38) ALDH1A1KMT2AHPGDLMNAMEN1
SCHEMBL11004596 0.74 PKM (0.41) ALDH1A1MAPTKMT2ACNR1PPARG
SCHEMBL11560424 0.74 KMT2A (0.40) ALDH1A1MAPTKMT2AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150499-A2 Substituted 3-azolyl butane derivatives, process for their preparation and agricultural and horticultural fungicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-08-07 EP disclosed