Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513046 | 0.83 | POLB (0.39) | KMT2AMEN1MAPK1PDK1PDK2 | |
| SCHEMBL11845929 | 0.76 | LMNA (0.39) | KMT2AMEN1MAPK1POLBALDH1A1 | |
| SCHEMBL11511178 | 0.76 | TSHR (0.42) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL11511837 | 0.76 | SMN1; SMN2 (0.51) | KMT2AMEN1MAPK1ALDH1A1HPGD | |
| SCHEMBL11512850 | 0.76 | GAA (0.41) | KMT2AMEN1PDK1PDK2PDK3 | |
| SCHEMBL30407917 | 0.75 | MRGPRX4 (0.38) | KMT2AHTR1DALDH1A1HPGDMAPT | |
| SCHEMBL11513712 | 0.74 | OGG1 (0.49) | KMT2APOLBALDH1A1HPGDMAPT | |
| SCHEMBL11005358 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL9672468 | 0.73 | CYP2D6 (0.42) | KMT2AMEN1HTR1DALDH1A1HPGD | |
| SCHEMBL11751450 | 0.73 | KMT2A (0.40) | KMT2AMEN1MAPK1HTR1DPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147791-A | 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4048318-A | 1-Substituted-1,2,4-triazole fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |