Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178066 | 0.80 | HTR1A (0.48) | CYP3A4CYP2A6HTR1DHTR2AHTR2C | |
| SCHEMBL22299626 | 0.80 | CYP2A6 (0.49) | CYP3A4CYP2A6HTR2AGPR84STING1 | |
| SCHEMBL27469930 | 0.75 | EIF2AK2 (0.51) | CYP3A4HTR2AGPR84STING1MEN1 | |
| SCHEMBL28087844 | 0.75 | HTR2A (0.51) | CYP3A4CYP2A6MPOCYP1A2CYP2D6 | |
| SCHEMBL701071 | 0.74 | GPR84 (0.47) | CYP3A4CYP2A6MPOCYP1A2CYP2D6 | |
| SCHEMBL1260955 | 0.74 | HTR2A (0.51) | CYP3A4CYP2D6HTR2AHTR6GPR84 | |
| SCHEMBL30753171 | 0.74 | HTR2A (0.51) | CYP3A4CYP2D6HTR2AHTR6GPR84 | |
| Acrylic Acid SCHEMBL23883385 | 0.72 | STING1 (0.45) | NFKB1HTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL2278702 | 0.71 | KDR (0.52) | CYP3A4GPR84STING1MEN1MAPT | |
| SCHEMBL29611671 | 0.71 | HTR2A (0.49) | CYP3A4HTR2AGPR84STING1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544663-A | ASPERMATOGENESIS INDUCERS | SANDOZ, INC. (US) | 1985-10-01 | — | — | US | disclosed |