Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | GABRE | P78334 | 1/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744669 | 0.87 | STING1 (0.52) | KDRKMT2AMEN1GABRPGABRD | |
| SCHEMBL31744872 | 0.81 | LMNA (0.48) | KDRKMT2AMEN1IDO1LMNA | |
| SCHEMBL31744619 | 0.81 | PTPRF (0.55) | KDRKMT2AMEN1GABRPGABRD | |
| SCHEMBL701071 | 0.78 | GPR84 (0.47) | KMT2AMEN1HSD17B10CYP3A4MAPT | |
| SCHEMBL30753171 | 0.78 | HTR2A (0.51) | KMT2AMEN1IDO1HSD17B10CYP3A4 | |
| SCHEMBL1260955 | 0.78 | HTR2A (0.51) | KMT2AMEN1IDO1HSD17B10CYP3A4 | |
| SCHEMBL29577526 | 0.76 | GPR84 (0.51) | KMT2AMEN1GABRPGABRDGABRA1 | |
| SCHEMBL7311206 | 0.76 | GPR84 (0.51) | KMT2AMEN1GABRPGABRDGABRA1 | |
| SCHEMBL7507194 | 0.75 | HTR2A (0.49) | KMT2AMEN1IDO1HSD17B10CYP3A4 | |
| SCHEMBL29611671 | 0.75 | HTR2A (0.49) | KMT2AMEN1IDO1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | claimed |
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | claimed |
| CN-114920775-A | Axial chiral bisindole catalyst and synthesis method and application thereof | 江苏师范大学 | 2022-08-19 | — | — | CN | claimed |
| CN-101747321-B | Indole-3-benzylamine derivative, preparation method and application | UNIV ZHEJIANG | 2013-01-02 | — | — | CN | claimed |
| CN-101747321-A | Indole-3-benzylamine derivative, preparation method and application | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | claimed |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CFD RES CORPORATION (US) | 2025-12-18 | — | — | US | disclosed |
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114920775-B | Axial chiral bisindole catalyst and synthetic method and application thereof | 江苏师范大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114920775-A | Axial chiral bisindole catalyst and synthesis method and application thereof | 江苏师范大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114920775-A | Axial chiral bisindole catalyst and synthesis method and application thereof | 江苏师范大学 | 2022-08-19 | — | — | CN | disclosed |
| EP-2367812-B1 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4TRIFLUOROMETHOXY-1H-INDOL-3-YL]METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI SA (FR) | 2015-09-16 | — | — | EP | disclosed |
| US-20110201647-A1 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI-AVENTIS (FR) | 2011-08-18 | — | — | US | disclosed |
| CN-102149705-A | [4- (5-aminomethyl-2-fluorophenyl) -piperidin-1-yl ] - [ 7-fluoro-1- (2-methoxyethyl) -4-trifluoromethoxy-1H-indol-3-yl ] -methanone as mast cell tryptase inhibitor | SANOFI AVENTIS | 2011-08-10 | — | — | CN | disclosed |
| WO-2010022196-A3 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI-AVENTIS (FR) | 2010-07-22 | — | — | WO | disclosed |
| CN-101747321-A | Indole-3-benzylamine derivative, preparation method and application | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | disclosed |
| CN-101747321-A | Indole-3-benzylamine derivative, preparation method and application | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | disclosed |
| CN-101747321-A | Indole-3-benzylamine derivative, preparation method and application | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | disclosed |
| WO-2010022196-A2 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI-AVENTIS (FR) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010022196-A2 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI-AVENTIS (FR) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201647-A1 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | CMA1, TPSAB1, TPSB2 | KDR 3726/4885KMT2A 1161/4885MEN1 2128/4885 |
| US-20250382269-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | KDR 4699/4885KMT2A 4633/4885MEN1 2402/4885 |
| US-20250382268-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES | CD14, MIF, NOD2 | KDR 4699/4885KMT2A 4633/4885MEN1 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.