Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463867 | 0.81 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL5069125 | 0.74 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL14827588 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL5732376 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL28062749 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL147771 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL7285376 | 0.73 | MEN1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL7197213 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL18461270 | 0.73 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL10036791 | 0.72 | LMNA (0.50) | ALDH1A1POLBHTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543355-A | Substituted succinimides, compositions and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-24 | — | — | US | disclosed |
| US-4507303-A | Succinimide derivatives, compositions and method of use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| EP-0082402-A2 | Succinimide derivates and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-29 | — | — | EP | disclosed |