SCHEMBL7285376

SCHEMBL7285376

O=COC(=O)C1C2CCC(C2)C1C(=O)OC=O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A3 Q01959 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21508160 0.79
SCHEMBL6437296 0.77 HSD11B1 (0.39) CYP2C9
SCHEMBL11007010 0.73 ALDH1A1 (0.42) ALDH1A1LMNA
SCHEMBL11010433 0.73 PPM1B (0.50) MEN1ALDH1A1KMT2ASLC6A3LMNA
SCHEMBL21174561 0.73 POLB (0.46) MEN1ALDH1A1KMT2A
SCHEMBL6939540 0.72 ELANE (0.34) MEN1KMT2A
SCHEMBL11239979 0.72
SCHEMBL6451745 0.72 CHRNB2 (0.32)
SCHEMBL24831831 0.70
SCHEMBL14216523 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0196096-B1 IMIDE DERIVATIVES, THEIR PRODUCTION AND USE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-04-22 EP disclosed
EP-0261688-B1 IMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-03-25 EP disclosed
US-4948799-A ANTIPSYCHOTIC DRUGS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1990-08-14 US disclosed
US-4745117-A NEUROLEPTIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1988-05-17 US disclosed
US-4543355-A Substituted succinimides, compositions and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-24 US disclosed
US-4507303-A Succinimide derivatives, compositions and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-03-26 US disclosed
EP-0082402-A2 Succinimide derivates and process for preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-06-29 EP disclosed