Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.51 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23695580 | 0.94 | GPR84 (0.52) | GPR84KAT8PPARACTSVCTSL | |
| SCHEMBL7069908 | 0.86 | LMNA (0.50) | GPR84CTSVCTSLHTR1AHTR1D | |
| SCHEMBL7074282 | 0.84 | LMNA (0.51) | GPR84CTSVCTSLHTR1AHTR1D | |
| SCHEMBL2056333 | 0.82 | KDM4E (0.54) | GPR84KDM4EALDH1A1 | |
| SCHEMBL2267028 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1 | |
| SCHEMBL12100781 | 0.80 | HTR1A (0.57) | KAT8PPARACTSVCTSLHTR1A | |
| SCHEMBL4581413 | 0.80 | HTR1A (0.57) | KAT8PPARACTSVCTSLHTR1A | |
| SCHEMBL12795553 | 0.80 | HTR1A (0.57) | KAT8PPARACTSVCTSLHTR1A | |
| SCHEMBL1128166 | 0.80 | HTR1A (0.57) | KAT8PPARACTSVCTSLHTR1A | |
| SCHEMBL31410497 | 0.80 | HTR1A (0.57) | KAT8PPARACTSVCTSLHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526894-A | Antiinflammatory agents | NIPPON SHINYAKU CO. LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0101330-A2 | 2-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-22 | — | — | EP | disclosed |