Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007109 | 0.94 | GPR84 (0.51) | GPR84KDM4EALDH1A1CTSVCTSL | |
| SCHEMBL2056333 | 0.84 | KDM4E (0.54) | GPR84KDM4EALDH1A1ARHPGD | |
| SCHEMBL2267028 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1ARHTTHPGD | |
| SCHEMBL17505168 | 0.81 | ALDH1A1 (0.44) | GPR84KDM4EALDH1A1ARHPGD | |
| SCHEMBL7074282 | 0.81 | LMNA (0.51) | GPR84KDM4EALDH1A1ARCTSV | |
| SCHEMBL7069908 | 0.79 | LMNA (0.50) | GPR84KDM4EALDH1A1ARCTSV | |
| SCHEMBL23695579 | 0.79 | MEN1 (0.56) | GPR84KDM4EALDH1A1CTSVCTSL | |
| SCHEMBL4323287 | 0.79 | HTR1A (0.54) | GPR84KDM4EALDH1A1CTSVCTSL | |
| SCHEMBL31108179 | 0.79 | HTR1A (0.54) | GPR84KDM4EALDH1A1CTSVCTSL | |
| SCHEMBL22990153 | 0.77 | HSD17B10 (0.47) | GPR84KDM4EALDH1A1HTR1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210837-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF VIRAL DISEASES | CRESCENTA BIOSCIENCES (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230210837-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF VIRAL DISEASES | CRESCENTA BIOSCIENCES (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2023-06-15 | — | — | US | disclosed |
| WO-2022010948-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF VIRAL DISEASES | CRESCENTA BIOSCIENCES (US) | 2022-01-13 | — | — | WO | disclosed |
| WO-2021150645-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210837-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF VIRAL DISEASES | FABP4, FABP1, FABP2 | GPR84 416/4885KDM4E 3130/4885ALDH1A1 1444/4885 |
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | FABP4, FABP1, FABP3 | GPR84 289/4885KDM4E 2557/4885ALDH1A1 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.