Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003881 | 0.84 | GRN (0.41) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL10645403 | 0.81 | MAPT (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL11005569 | 0.79 | LMNA (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11007121 | 0.76 | ACE (0.51) | — | |
| SCHEMBL4579585 | 0.75 | ITGB1 (0.42) | KMT2AMEN1IRAK4MAPK1MGLL | |
| SCHEMBL31124633 | 0.75 | ITGB1 (0.42) | KMT2AMEN1IRAK4MAPK1MGLL | |
| SCHEMBL31124620 | 0.75 | ITGB1 (0.42) | KMT2AMEN1IRAK4MAPK1MGLL | |
| SCHEMBL10650169 | 0.74 | ITGB1 (0.41) | KMT2AMEN1IRAK4MAPK1MGLL | |
| SCHEMBL27353938 | 0.74 | MGLL (0.37) | ALDH1A1IRAK4MGLL | |
| SCHEMBL9646362 | 0.73 | TDP1 (0.39) | MAPTIRAK4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525476-A | TREATING SENILITY OR AMNESIA | WARNER-LAMBERT COMPANY (US) | 1985-06-25 | — | — | US | claimed |
| US-4525476-A | TREATING SENILITY OR AMNESIA | WARNER-LAMBERT COMPANY (US) | 1985-06-25 | — | — | US | disclosed |