SCHEMBL11007604

SCHEMBL11007604

C=C(CCl)c1cccc2ccccc12.C=C(c1ccccc1C(=C)C(C)Cl)C(C)Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
PTPN1 P18031 1/20 0.37
PLK1 P53350 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 2/20 0.36
GMNN O75496 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
BLM P54132 2/20 0.36
PMP22 Q01453 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9385109 0.86 PTK2B (0.50) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL9051012 0.77 ALDH1A1 (0.35) L3MBTL1ALDH1A1LMNAMAPTKMT2A
SCHEMBL2098307 0.72 PTK2B (0.50) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL5125965 0.71 NR4A1 (0.57) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL7196206 0.71 PTK2B (0.49) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL20398171 0.70 L3MBTL1 (0.52) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL10581635 0.69 PTK2B (0.50) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL13963143 0.69 PTPN1 (0.61) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL31470908 0.68 NR4A1 (0.41) PTK2BL3MBTL1NR4A1NR4A2NR4A3
SCHEMBL28669828 0.67 L3MBTL1 (0.49) PTK2BL3MBTL1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161373-A1 Aqueous adhesive for bonding rubber by vulcanisation to a substrate Henkel Kommanditgesellschaft auf Aktien (DE) 1985-11-21 EP disclosed