Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12339828 | 0.81 | CA2 (0.36) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1176930 | 0.77 | CYP1A2 (0.45) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17773091 | 0.75 | TDP1 (0.50) | CA2CA1ALOX5TDP1EPHX2 | |
| SCHEMBL27507404 | 0.74 | CA2 (0.48) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19077753 | 0.74 | PTPN1 (0.42) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1826843 | 0.72 | CYP2C9 (0.41) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13435350 | 0.72 | ALOX15 (0.43) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1052797 | 0.71 | TDP1 (0.39) | ALOX5PTGS2TDP1CYP3A4ALDH1A1 | |
| SCHEMBL16997139 | 0.69 | ADRA2A (0.49) | CA2CA1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9757757 | 0.69 | TDP1 (0.43) | CA2CA1ALOX5PTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135792-A2 | Copolyester-carbonate compositions exhibiting improved processability | GENERAL ELECTRIC COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4487896-A | Copolyester-carbonate compositions exhibiting improved processability | GENERAL ELECTRIC COMPANY (US) | 1984-12-11 | — | — | US | disclosed |