SCHEMBL13435350

SCHEMBL13435350

COc1c(C)cc(C(C)(C)c2cc(C)c(O)c(C)c2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX12 P18054 2/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
RECQL P46063 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
ALOX5 P09917 2/20 0.38
PTGS1 P23219 2/20 0.38
PTGS2 P35354 2/20 0.38
GPR35 Q9HC97 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16808028 0.89 CA1 (0.42) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL14749884 0.89 PTPN1 (0.46) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL12325400 0.89 ESR1 (0.39) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL69586 0.84 ALDH1A1 (0.56) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL14998829 0.84 DHFR (0.42) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL2618674 0.82 ALDH1A1 (0.54) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL29472991 0.82 ALDH1A1 (0.54) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL19596581 0.80 CA1 (0.67) ALDH1A1TDP1CYP3A4ESR1ESR2
SCHEMBL17880000 0.80 PTPN1 (0.44) ALOX15ALDH1A1TDP1CYP3A4ALOX12
SCHEMBL677498 0.80 PTPN1 (0.44) ALOX15ALDH1A1TDP1CYP3A4ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374300-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR MANUFACTURING PLATED MOLDED ARTICLE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2023-11-23 US disclosed
US-11505699-B2 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-11-22 US disclosed
US-20170267807-A1 POLYPHENYLENE ETHER MODIFIED PHENOL-BENZALDEHYDE MULTIFUNCTIONAL EPOXY RESIN AND USE NAN YA PLASTICS CORPORATION (TW) 2017-09-21 US disclosed
US-20170267807-A1 POLYPHENYLENE ETHER MODIFIED PHENOL-BENZALDEHYDE MULTIFUNCTIONAL EPOXY RESIN AND USE NAN YA PLASTICS CORPORATION (TW) 2017-09-21 US disclosed
WO-2013028719-A1 POLYETHERIMIDE COMPOSITIONS AND METHODS FOR THE MANUFACTURE AND USE THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-02-28 WO disclosed
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US disclosed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US disclosed
US-7541421-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-02 US disclosed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US disclosed