Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | EDNRA | P25101 | 1/20 | 0.67 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904141 | 0.92 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11013455 | 0.91 | LMNA (0.69) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11006503 | 0.88 | LMNA (0.81) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9147435 | 0.85 | LMNA (0.58) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8044673 | 0.83 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9044893 | 0.83 | KMT2A (0.67) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9775969 | 0.83 | ALDH1A1 (0.67) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11153426 | 0.83 | LMNA (0.82) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11196749 | 0.83 | LMNA (0.56) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11198791 | 0.83 | LMNA (0.56) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57106681-A | — | — | None | — | — | JP | disclosed |
| US-4496566-A | ANTIBACTERIAL AGENT | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1985-01-29 | — | — | US | disclosed |
| JP-S57106681-A | 1,8-NAPHTHYRIDINE DERIVATIVE AND ITS SALT | DAINIPPON PHARMACEUT CO LTD | 1982-07-02 | — | — | JP | disclosed |