Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16450335 | 0.81 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL29471771 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11153077 | 0.81 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL43770 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11149177 | 0.75 | ALDH1A1 (0.75) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11149089 | 0.75 | ALDH1A1 (0.71) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11149202 | 0.74 | ALDH1A1 (0.70) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11146576 | 0.74 | ALDH1A1 (0.70) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL9040334 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11154799 | 0.72 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503052-A | OXACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |