Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 4/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.32 |
| ▸ | GRB2 | P62993 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359592 | 0.80 | ACE (0.39) | ACEMMP1GRB2 | |
| SCHEMBL28830127 | 0.79 | CPB2 (0.41) | ACECPB2MMP2MMP8MMP1 | |
| SCHEMBL28830126 | 0.79 | CPB2 (0.41) | ACECPB2MMP2MMP8MMP1 | |
| SCHEMBL11012174 | 0.79 | ACE (0.43) | ACEMMP1RENCDK4CCNA2 | |
| SCHEMBL30496934 | 0.78 | SLC6A5 (0.44) | ACE | |
| SCHEMBL29640354 | 0.78 | SLC6A5 (0.44) | ACE | |
| SCHEMBL29640332 | 0.78 | SLC6A5 (0.44) | ACE | |
| SCHEMBL30496953 | 0.78 | SLC6A5 (0.44) | ACE | |
| SCHEMBL31020879 | 0.78 | ACE (0.38) | ACEMMP1REN | |
| SCHEMBL10431448 | 0.78 | ACE (0.33) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |