Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419274 | 0.90 | ALDH1A1 (0.52) | NAMPTMAOAMAOBALDH1A1BCHE | |
| SCHEMBL11010091 | 0.83 | MAOA (0.52) | MAOAMAOBALDH1A1BCHEADRA2B | |
| Hydrochloric Acid SCHEMBL9725935 | 0.82 | MAOA (0.51) | MAOAMAOBALDH1A1BCHEADRA2B | |
| SCHEMBL6923878 | 0.78 | MAOA (0.59) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL172566 | 0.77 | MAOA (0.60) | MAOAMAOBBCHEADRA2BADRA2C | |
| SCHEMBL11005532 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL11012783 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL12269128 | 0.74 | HTR2C (0.55) | HTR2CSLC6A3MAOAMAOBALDH1A1 | |
| SCHEMBL917662 | 0.74 | MAOA (0.60) | HTR2CSLC6A3MAOAMAOBALDH1A1 | |
| SCHEMBL918896 | 0.74 | MAOA (0.60) | HTR2CSLC6A3MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2023-04-25 | — | — | US | disclosed |
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2020-02-27 | — | — | US | disclosed |
| WO-2018045464-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | SNCA, PARK7, SYNJ2 | NAMPT 3421/4885HTR2C 2631/4885SLC6A3 229/4885 |
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | SNCA, PARK7, SYNJ2 | NAMPT 3421/4885HTR2C 2631/4885SLC6A3 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.