Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449241 | 1.00 | ADRA1A (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL28054318 | 0.88 | ADRA1A (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL28456741 | 0.86 | KDM4E (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL28456745 | 0.86 | KDM4E (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL4599810 | 0.84 | ADRA2A (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11219994 | 0.79 | ALDH1A1 (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL11420697 | 0.79 | ALDH1A1 (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD | |
| SCHEMBL7917672 | 0.79 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL11009168 | 0.74 | MTNR1A (0.38) | CYP1A2ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL11123894 | 0.73 | ALDH1A1 (0.38) | ADRA1ACYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646925-A | Amrubicin hydrochloride intermediate compound | 鲁南制药集团股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111646928-A | Aminorubicin hydrochloride intermediate compound I-2 | 鲁南制药集团股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111646915-A | Amrubicin hydrochloride intermediate compound I | 鲁南制药集团股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111646924-A | Aminorubicin hydrochloride intermediate compound I-4 | 鲁南制药集团股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-4540695-A | Aminonaphthacene derivatives and their use | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0072259-B1 | AMINONAPHTHACENE DERIVATIVES, THEIR PRODUCTION AND ANTI-TUMOR OR ANTI-MICROBIAL COMPOSITIONS CONTAINING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-21 | — | — | EP | disclosed |
| EP-0072259-A1 | Aminonaphthacene derivatives, their production and anti-tumor or anti-microbial compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-02-16 | — | — | EP | disclosed |