SCHEMBL11010679

SCHEMBL11010679

O=[N+]([O-])c1cccc2nn(-c3cc(O)ccc3O)cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 6/20 0.41
CTSB P07858 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
BRD4 O60885 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD2 P14416 1/20 0.41
ALOX12 P18054 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2C P28335 1/20 0.41
CTH P32929 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11011692 0.81 NOS1 (0.52) MEN1KMT2AALDH1A1CTSBTDP1
SCHEMBL11012636 0.75 MEN1 (0.60) MEN1KMT2AALDH1A1TDP1MAPT
SCHEMBL11014378 0.74 MEN1 (0.49) MEN1KMT2AALDH1A1TDP1MAPT
SCHEMBL11007018 0.72 ESR2 (0.54) MEN1KMT2AALDH1A1MAPTRAB9A
SCHEMBL4719658 0.71 ALDH1A1 (0.59) MEN1KMT2AALDH1A1TDP1MAPT
SCHEMBL4197934 0.70 NOS1 (0.58) MEN1KMT2AALDH1A1TDP1MAPT
SCHEMBL3656023 0.67 ALDH1A1 (0.48) MEN1KMT2AALDH1A1TDP1MAPT
SCHEMBL2934866 0.67 ALDH1A1 (0.61) MEN1KMT2AALDH1A1CTSBTDP1
SCHEMBL2170070 0.67 ALDH1A1 (0.61) MEN1KMT2AALDH1A1CTSBTDP1
SCHEMBL1716412 0.66 POLB (0.57) MEN1KMT2AALDH1A1CTSBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4501898-A Photographic development inhibitor (1H- or 2H-) indazolyl hydroquinone derivatives FUJI PHOTO FILM CO., LTD. (JP) 1985-02-26 US disclosed
US-4345024-A A 3-INDAZOL-1 OR 2-YL HYDROQUINONE DERIVATIVE IN A PHOTOSENSITIVE SILVER HALIDE EMULSION; COLOR FILMS; BLACK AND WHITE PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1982-08-17 US disclosed