Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015134 | 0.81 | MEN1 (0.45) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL11169022 | 0.76 | PTPN11 (0.58) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL11013779 | 0.73 | PTPN11 (0.48) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL11012050 | 0.72 | MEN1 (0.50) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL11008836 | 0.69 | TP53 (0.52) | PDK1PDK2PDK3PDK4PTPN11 | |
| SCHEMBL10673371 | 0.69 | TP53 (0.55) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL10664268 | 0.68 | KMT2A (0.59) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL9407041 | 0.67 | MEN1 (0.44) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL11164935 | 0.67 | RAB9A (0.55) | MEN1KMT2ARAB9ATDP1PKM | |
| SCHEMBL10425911 | 0.67 | ALDH1A1 (0.57) | MEN1KMT2ARAB9ATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4519834-A | Herbicidal ethynyl-phenylureas | CIBA-GEIGY CORPORATION (US) | 1985-05-28 | — | — | US | claimed |