Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008836 | 0.87 | TP53 (0.52) | EGFRLMNAL3MBTL1PTPN11PDK1 | |
| SCHEMBL11169022 | 0.84 | PTPN11 (0.58) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11012233 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11013779 | 0.81 | PTPN11 (0.48) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11012050 | 0.80 | MEN1 (0.50) | MEN1KMT2AEGFRTDP1PKM | |
| SCHEMBL845317 | 0.80 | GRM5 (0.52) | MEN1KMT2AEGFRRAB9AL3MBTL1 | |
| SCHEMBL10673371 | 0.76 | TP53 (0.55) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11164935 | 0.74 | RAB9A (0.55) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL10425911 | 0.74 | ALDH1A1 (0.57) | MEN1KMT2ATDP1PKMRAB9A | |
| SCHEMBL11195584 | 0.73 | MEN1 (0.52) | MEN1KMT2ATDP1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4519834-A | Herbicidal ethynyl-phenylureas | CIBA-GEIGY CORPORATION (US) | 1985-05-28 | — | — | US | claimed |