Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015134 | 0.87 | MEN1 (0.45) | TP53PTPN11PDK1PDK2PDK3 | |
| SCHEMBL845317 | 0.84 | GRM5 (0.52) | TP53PTPN11PDK1PDK2PDK3 | |
| SCHEMBL4610082 | 0.78 | ALDH1A1 (0.60) | TP53PNPLA2HDAC6PDK1PDK2 | |
| SCHEMBL13400502 | 0.77 | KCNK3 (0.50) | EGFRLMNAL3MBTL1 | |
| SCHEMBL2889973 | 0.77 | EGFR (0.49) | PTPN11PDK1PDK2PDK3PDK4 | |
| SCHEMBL31536232 | 0.77 | EGFR (0.49) | PTPN11PDK1PDK2PDK3PDK4 | |
| SCHEMBL19019393 | 0.77 | TP53 (0.69) | TP53PNPLA2HDAC6APEX1 | |
| SCHEMBL13132819 | 0.76 | L3MBTL1 (0.47) | LMNAL3MBTL1 | |
| SCHEMBL13023070 | 0.76 | LMNA (0.47) | PTPN11PDK1PDK2PDK3PDK4 | |
| SCHEMBL13132849 | 0.76 | SIRT1 (0.49) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4519834-A | Herbicidal ethynyl-phenylureas | CIBA-GEIGY CORPORATION (US) | 1985-05-28 | — | — | US | claimed |