Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7705481 | 0.98 | MAPT (0.66) | MAPTKDM4ELMNARAB9ANPC1 | |
| Oxyquinoline SCHEMBL11594833 | 0.90 | MMP2 (0.66) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL14825073 | 0.87 | MAPT (0.70) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL19733317 | 0.86 | MAPT (0.54) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL2484526 | 0.85 | MAPT (0.66) | MAPTKDM4ELMNARAB9ANPC1 | |
| Imidazole SCHEMBL28294375 | 0.85 | MAPT (0.53) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL2484185 | 0.84 | MAPT (0.68) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL18816623 | 0.83 | MAPT (0.69) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL9568616 | 0.82 | MAPT (0.66) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL9671193 | 0.82 | MAPT (0.53) | MAPTKDM4ELMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670180-A | Fluoroalkenyl compounds, process for their preparation and their use | PI工业有限公司 | 2020-09-15 | — | — | CN | claimed |
| EP-2265677-B1 | CORROSION DETECTION PRODUCT AND METHOD | BATTELLE MEMORIAL INSTITUTE (US) | 2019-05-15 | — | — | EP | claimed |
| EP-2084163-B1 | TETRACYCLIC INHIBITORS OF CYSTEINE PROTEASES, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2017-04-12 | — | — | EP | claimed |
| EP-2039685-B1 | Heterobicyclic compounds as P38 inhibitors | ARRAY BIOPHARMA INC (US) | 2012-12-26 | — | — | EP | claimed |
| US-8153791-B2 | substituted pyrimidine compoundssuch as 4-amino-6-(3-chloro-4-fluoro-phenylamino)-pyrimidine-5-carbaldehyde O-methyl oxime, used for treating, preventing or ameliorating a chronic or acute protein kinase mediated diseasea, disorders or conditions | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-10 | — | — | US | claimed |
| CN-101941964-A | Has the Chemokine Receptors bonded heterogeneous ring compound that promotes effect | ANORMED INC | 2011-01-12 | — | — | CN | claimed |
| JP-4267920-B2 | — | — | 2009-05-27 | — | — | JP | claimed |
| CN-100376604-C | Olefin polymerization catalyst and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2008-03-26 | — | — | CN | claimed |
| US-20070270425-A1 | SUBSTITUTED PYRIMIDINYL OXIME KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-22 | — | — | US | claimed |
| CN-1769307-A | Olefin polymerization catalyst and its uses | CHINA PETROLEUM & CHEMICAL (CN) | 2006-05-10 | — | — | CN | claimed |
| US-6194422-B1 | ANTIBIOTIC; AMYLOIDOSES THERAPY | PHARMACIA & UPJOHN SPA (IT) | 2001-02-27 | — | — | US | claimed |
| EP-0970080-A1 | IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-12 | — | — | EP | claimed |
| WO-1998032754-A1 | IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-07-30 | — | — | WO | claimed |
| EP-0445731-B1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER LAMBERT CO (US) | 1996-01-10 | — | — | EP | claimed |
| US-5482938-A | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | claimed |
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | claimed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | claimed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | claimed |
| US-4786648-A | ANALGESIC | WARNER-LAMBERT COMPANY (US) | 1988-11-22 | — | — | US | claimed |
| EP-0271798-A2 | O-Substituted tetrahydropyridine oxime cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-06-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270425-A1 | SUBSTITUTED PYRIMIDINYL OXIME KINASE INHIBITORS | MAP3K2, MAP3K1, MAP3K20 | MAPT 3084/4885KDM4E 1680/4885LMNA 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.