Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101347 | 0.85 | MAPT (0.68) | MAPTLMNAKDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7705481 | 0.83 | MAPT (0.66) | MAPTLMNAKDM4ERAB9ANPC1 | |
| Phenanthroline SCHEMBL25421956 | 0.78 | LMNA (0.61) | MAPTLMNAKDM4EMEN1KMT2A | |
| Oxyquinoline SCHEMBL11594833 | 0.77 | MMP2 (0.66) | MAPTLMNAKDM4ERAB9ANPC1 | |
| Oxyquinoline SCHEMBL30108907 | 0.75 | TSHR (0.68) | MAPTLMNAKDM4ERAB9ANPC1 | |
| Oxyquinoline SCHEMBL9905752 | 0.75 | TSHR (0.68) | MAPTLMNAKDM4ERAB9ANPC1 | |
| SCHEMBL14825073 | 0.74 | MAPT (0.70) | MAPTLMNAKDM4ERAB9ANPC1 | |
| SCHEMBL19733317 | 0.73 | MAPT (0.54) | MAPTLMNAKDM4ERAB9ANPC1 | |
| SCHEMBL2484526 | 0.72 | MAPT (0.66) | MAPTLMNAKDM4ERAB9ANPC1 | |
| Quinoline SCHEMBL27593554 | 0.72 | ALDH1A1 (0.55) | MAPTLMNAKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776500-A | A kind of double 8-hydroxyquinoline ligands of 1- tolimidazole bridging, Zn complex and its preparation method and application | 广州工程技术职业学院 | 2019-05-21 | — | — | CN | disclosed |