Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441309 | 0.81 | ITGB3 (0.46) | REN | |
| SCHEMBL11013722 | 0.80 | REN (0.58) | REN | |
| SCHEMBL9716892 | 0.79 | REN (0.65) | REN | |
| SCHEMBL11012331 | 0.78 | REN (0.51) | RENF2 | |
| SCHEMBL30599003 | 0.78 | CCNA2 (0.51) | — | |
| SCHEMBL9716847 | 0.77 | REN (0.66) | RENCTSD | |
| SCHEMBL16508044 | 0.76 | PSMB5 (0.49) | RENCTSDF2 | |
| SCHEMBL31746151 | 0.75 | F2 (0.47) | RENCTSDF2 | |
| SCHEMBL24919552 | 0.75 | NPY4R (0.57) | — | |
| SCHEMBL11018761 | 0.75 | REN (0.67) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | claimed |