SCHEMBL11014099

CC[C@H](C)[C@H](NC(=O)[C@@H](NC[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(N)=O

nearest known ligand 0.58

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	12/20	0.58

▸	BACE1	P56817	6/20	0.52

▸	CTSD	P07339	2/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9716892	0.86	REN (0.65)	REN
SCHEMBL11015609	0.86	REN (0.56)	RENCTSD
SCHEMBL10664115	0.84	REN (0.62)	REN
SCHEMBL10664132	0.84	REN (0.62)	REN
SCHEMBL11007909	0.83	REN (0.56)	RENCTSD
SCHEMBL11011996	0.83	REN (0.57)	REN
SCHEMBL10656796	0.83	REN (0.57)	REN
SCHEMBL10656802	0.83	REN (0.57)	REN
SCHEMBL11014015	0.82	REN (0.47)	RENCTSD
SCHEMBL10630585	0.82	REN (0.63)	RENCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0144290-A2	Substituted ethylenediamine derivatives	CIBA-GEIGY AG (CH)	1985-06-12	—	—	EP	claimed