Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.57 |
| ▸ | CTSB | P07858 | 6/20 | 0.52 |
| ▸ | CTSK | P43235 | 6/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007909 | 0.90 | REN (0.56) | REN | |
| SCHEMBL11014015 | 0.89 | REN (0.47) | REN | |
| SCHEMBL11015609 | 0.85 | REN (0.56) | REN | |
| SCHEMBL11013919 | 0.85 | REN (0.66) | RENCTSBCTSK | |
| SCHEMBL11010625 | 0.85 | REN (0.66) | RENCTSBCTSK | |
| SCHEMBL9716847 | 0.84 | REN (0.66) | RENCTSBCTSK | |
| SCHEMBL11014099 | 0.83 | REN (0.58) | REN | |
| SCHEMBL11012331 | 0.82 | REN (0.51) | RENCTSBCTSKPTPN1PSMB1 | |
| SCHEMBL10909548 | 0.81 | CTSB (0.53) | RENCTSBCTSK | |
| SCHEMBL10636524 | 0.81 | CTSK (0.54) | RENCTSBCTSKPTPN1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | claimed |