Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014015 | 0.92 | REN (0.47) | RENCTSD | |
| SCHEMBL11011996 | 0.90 | REN (0.57) | REN | |
| SCHEMBL11015609 | 0.86 | REN (0.56) | RENCTSD | |
| SCHEMBL11014099 | 0.83 | REN (0.58) | RENCTSD | |
| SCHEMBL11014003 | 0.79 | REN (0.47) | RENCTSD | |
| SCHEMBL7278620 | 0.76 | REN (0.47) | REN | |
| SCHEMBL9417336 | 0.76 | REN (0.48) | REN | |
| SCHEMBL11037671 | 0.76 | CTSD (0.48) | RENCTSD | |
| SCHEMBL9716892 | 0.76 | REN (0.65) | REN | |
| SCHEMBL11010625 | 0.75 | REN (0.66) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | claimed |