SCHEMBL11014445

SCHEMBL11014445

Nc1c(C(=O)NO)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.69
MEN1 O00255 8/20 0.69
KMT2A Q03164 8/20 0.69
MAPK1 P28482 7/20 0.69
ALDH1A1 P00352 7/20 0.69
THRB P10828 3/20 0.69
POLB P06746 3/20 0.69
LMNA P02545 2/20 0.69
RECQL P46063 2/20 0.69
L3MBTL1 Q9Y468 3/20 0.57
PKM P14618 3/20 0.57
MCL1 Q07820 3/20 0.57
NPSR1 Q6W5P4 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.56
KDM4E B2RXH2 3/20 0.56
MMP14 P50281 1/20 0.56
MAOA P21397 2/20 0.56
MAOB P27338 1/20 0.56
CYP3A4 P08684 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839419 0.82 MAPT (1.00) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8941899 0.82 MAPT (0.76) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL10327249 0.81 MAPT (0.61) MAPTMEN1KMT2AMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL11043762 0.81 MAPT (0.97) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8744278 0.81 MAPT (0.73) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL11043758 0.81 MAPT (0.73) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8941856 0.80 MAPT (0.71) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8770405 0.78 MAPT (0.74) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL11350345 0.77 MAPT (0.68) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL14095119 0.76 MAPK1 (0.59) MAPTMEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0134198-A1 Use of quinone derivatives for the protection of cultivated plants against the phytotoxic effects of herbicides CIBA-GEIGY AG (CH) 1985-03-13 EP claimed
EP-0134198-A1 Use of quinone derivatives for the protection of cultivated plants against the phytotoxic effects of herbicides CIBA-GEIGY AG (CH) 1985-03-13 EP disclosed