Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | THRB | P10828 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839419 | 0.85 | MAPT (1.00) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8941899 | 0.85 | MAPT (0.76) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11043762 | 0.83 | MAPT (0.97) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8744278 | 0.83 | MAPT (0.73) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11014445 | 0.81 | MAPT (0.69) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8770405 | 0.81 | MAPT (0.74) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11350345 | 0.80 | MAPT (0.68) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8941856 | 0.80 | MAPT (0.71) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8675450 | 0.79 | ALDH1A1 (0.70) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11760681 | 0.79 | MEN1 (0.74) | MAPTMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019285-B1 | PROCESS FOR PREPARING ASYMMETRICAL VAT DYESTUFFS OF THE ANTHRAQUINONE SERIES AND THEIR USE IN DYEING AND PRINTING | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| US-4329456-A | ACYLATION WITHOUT INTERMEDIATE ISOLATION | CIBA-GEIGY AG (CH) | 1982-05-11 | — | — | US | claimed |
| US-4329456-A | ACYLATION WITHOUT INTERMEDIATE ISOLATION | CIBA-GEIGY AG (CH) | 1982-05-11 | — | — | US | disclosed |
| US-4265633-A | Process for the manufacture of vat dyes | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |