SCHEMBL8770405

SCHEMBL8770405

Nc1c(C(=O)c2ccccc2)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.74
MEN1 O00255 8/20 0.74
KMT2A Q03164 8/20 0.74
MAPK1 P28482 7/20 0.74
ALDH1A1 P00352 7/20 0.74
THRB P10828 3/20 0.74
POLB P06746 3/20 0.74
LMNA P02545 3/20 0.74
RECQL P46063 1/20 0.74
NPSR1 Q6W5P4 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
PKM P14618 3/20 0.57
TDP1 Q9NUW8 2/20 0.57
MCL1 Q07820 2/20 0.57
KDM4E B2RXH2 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MMP14 P50281 1/20 0.56
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
CASP3 P42574 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839419 0.85 MAPT (1.00) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL28923230 0.84 MAPT (0.55) MAPTMEN1KMT2AMAPK1ALDH1A1
Hydrochloric Acid SCHEMBL11043762 0.84 MAPT (0.97) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8941899 0.82 MAPT (0.76) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL8744278 0.81 MAPT (0.73) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL11043758 0.81 MAPT (0.73) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL308358 0.80 ALDH1A1 (0.71) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL11742792 0.79 MAOA (0.57) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL9511849 0.79 ADORA2A (0.61) MAPTMEN1KMT2AMAPK1ALDH1A1
SCHEMBL28199522 0.78 MAOA (0.56) MAPTMEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7188138-A None JP disclosed
EP-0653416-B1 Process for the preparation of benzoyl amino anthraquinone compounds BASF AG (DE) 1997-09-24 EP disclosed
JP-H07188138-A PREPARATION OF BENZOYL AMINOANTHRAQUINONE COMPOUND BASF AG 1995-07-25 JP disclosed
EP-0653416-A1 Process for the preparation of benzoyl amino anthraquinone compounds BASF Aktiengesellschaft (DE) 1995-05-17 EP disclosed