Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238962 | 0.89 | NR3C2 (0.44) | NR3C2TLR8KDM4ENOS3NOS1 | |
| SCHEMBL31119421 | 0.82 | NOS3 (0.57) | NR3C2KDM4ENOS3NOS1NOS2 | |
| SCHEMBL2566737 | 0.82 | NOS3 (0.57) | NR3C2KDM4ENOS3NOS1NOS2 | |
| SCHEMBL29078768 | 0.80 | NR3C2 (0.50) | MMENR3C2KDM4E | |
| SCHEMBL5746344 | 0.79 | MME (0.41) | MMENR3C2SKP2TLR8KDM4E | |
| SCHEMBL18469854 | 0.78 | KDM4E (0.46) | MMENR3C2KDM4EHPGDMAPK1 | |
| SCHEMBL5746928 | 0.78 | NR3C2 (0.43) | MMENR3C2NPC1HPGDMAPK1 | |
| SCHEMBL22239778 | 0.78 | MME (0.47) | MMENR3C2NPC1RAB9A | |
| SCHEMBL6938337 | 0.77 | NOS2 (0.66) | SKP2TLR8KDM4ENOS3NOS1 | |
| SCHEMBL2993441 | 0.76 | SKP2 (0.44) | SKP2TLR8KDM4ENOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139917-A1 | Pharmaceutical preparations, acylated hydrazine derivatives, methods for their preparation | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | disclosed |