Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812604 | 0.81 | HPGDS (0.43) | KDM4EMAPTMAPK1ELANEHPGDS | |
| SCHEMBL11386187 | 0.81 | KDM4E (0.77) | KDM4EMAPTMAPK1ELANELMNA | |
| SCHEMBL19484789 | 0.81 | MAPT (0.78) | KDM4EMAPTMAPK1ELANECFD | |
| SCHEMBL5603081 | 0.80 | KDM4E (1.00) | KDM4EMAPTMAPK1ELANECFD | |
| SCHEMBL8050658 | 0.78 | PTGS2 (0.62) | KDM4EMAPK1CFDHPGDSLMNA | |
| SCHEMBL7941782 | 0.78 | KDM4E (0.72) | KDM4EMAPTMAPK1ELANECFD | |
| SCHEMBL14744132 | 0.78 | KDM4E (0.72) | KDM4EMAPTMAPK1ELANECFD | |
| SCHEMBL7952926 | 0.77 | KDM4E (0.70) | KDM4EMAPTMAPK1ELANELMNA | |
| SCHEMBL624930 | 0.77 | SMN1; SMN2 (0.61) | KDM4EMAPTHPGDSLMNANPC1 | |
| SCHEMBL29799615 | 0.77 | SMN1; SMN2 (0.61) | KDM4EMAPTHPGDSLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |