Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015630 | 0.81 | KDM4E (0.66) | HPGDSKDM4EELANEGSK3BHPGD | |
| SCHEMBL14812412 | 0.81 | KDM4E (0.51) | KDM4EELANEHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL29799615 | 0.78 | SMN1; SMN2 (0.61) | HPGDSKDM4EGSK3BHPGDSMN1; SMN2 | |
| SCHEMBL624930 | 0.78 | SMN1; SMN2 (0.61) | HPGDSKDM4EGSK3BHPGDSMN1; SMN2 | |
| SCHEMBL7398995 | 0.75 | ALDH1A1 (0.53) | HPGDSKDM4EGSK3BHSD17B10SMN1; SMN2 | |
| SCHEMBL5052478 | 0.74 | KDM4E (0.56) | HPGDSKDM4EGSK3BHPGDHSD17B10 | |
| SCHEMBL5057119 | 0.73 | KDM4E (0.69) | HPGDSKDM4EGSK3BHPGDHSD17B10 | |
| SCHEMBL7334423 | 0.72 | RXFP1 (0.49) | HPGDSGSK3BSMN1; SMN2LMNAHTT | |
| SCHEMBL28830235 | 0.72 | CA12 (0.57) | KDM4EHPGDSMN1; SMN2TP53LMNA | |
| SCHEMBL24263499 | 0.71 | HPGDS (0.51) | HPGDSKDM4EGSK3BHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969027-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3176156-B1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2019-06-12 | — | — | EP | disclosed |
| EP-2968100-B1 | COMBINATION OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES | BEIERSDORF AG (DE) | 2019-04-10 | — | — | EP | disclosed |
| US-10245252-B2 | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin | BEIERSDORF AG (DE) | 2019-04-02 | — | — | US | disclosed |
| EP-2969028-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV FILTER SUBSTANCES | BEIERSDORF AG (DE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3176156-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | Beiersdorf AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| US-9610234-B2 | Combinations of alkylamidothiazoles and preservatives | BEIERSDORF AG (DE) | 2017-04-04 | — | — | US | disclosed |
| EP-2758381-B1 | ALKYLAMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-9533963-B2 | Alkylamidothiazoles, cosmetic or dermatological preparations containing said alkylamidothiazoles, and use thereof to combat or prevent undesired pigmentation of the skin | BEIERSDORF AG (DE) | 2017-01-03 | — | — | US | disclosed |
| US-20160324832-A1 | USE OF ALKYLAMIDOTHIAZOLES IN COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS OR TREATMENT OF SENSITIVE SKIN | BEIERSDORF AG (DE) | 2016-11-10 | — | — | US | disclosed |
| WO-2014139741-A1 | COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND CYCLODEXTRINS | BEIERSDORF AG (DE) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014139758-A1 | COMPOSITIONS CONSISTING OF ALKYLAMIDOTHIAZOLES AND AROMATIC SUBSTANCES | BEIERSDORF AG (DE) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014139757-A1 | COMBINATIONS OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES | BEIERSDORF AG (DE) | 2014-09-18 | — | — | WO | disclosed |
| EP-2758381-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ALKYLAMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | Beiersdorf AG (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2758383-A1 | AROMATIC AMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID AROMATIC AMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | Beiersdorf AG (DE) | 2014-07-30 | — | — | EP | disclosed |
| EP-2758382-A1 | HETEROCYCLOCARBONYLAMINOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID HETEROCYCLOCARBONYLAMINOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | Beiersdorf AG (DE) | 2014-07-30 | — | — | EP | disclosed |
| US-20140121250-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ALKYLAMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2014-05-01 | — | — | US | disclosed |
| WO-2013041537-A1 | HETEROCYCLOCARBONYLAMINOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID HETEROCYCLOCARBONYLAMINOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013041535-A1 | AROMATIC AMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID AROMATIC AMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013041526-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ALKYLAMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121250-A1 | ALKYLAMIDOTHIAZOLES, COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING SAID ALKYLAMIDOTHIAZOLES, AND USE THEREOF TO COMBAT OR PREVENT UNDESIRED PIGMENTATION OF THE SKIN | TYR, PAH, NAT1 | HPGDS 3483/4885KDM4E 2444/4885ELANE 2401/4885 |
| US-10245252-B2 | Use of alkylamidothiazoles in cosmetic or dermatological preparations for the prophylaxis or treatment of sensitive skin | CUTA, TYR, AADAC | HPGDS 2704/4885KDM4E 4027/4885ELANE 48/4885 |
| US-20160324832-A1 | USE OF ALKYLAMIDOTHIAZOLES IN COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS OR TREATMENT OF SENSITIVE SKIN | CUTA, TYR, AADAC | HPGDS 2704/4885KDM4E 4027/4885ELANE 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.