Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016051 | 1.00 | RAB9A (0.58) | RAB9AKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL8828149 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL8828141 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL10669696 | 0.78 | KMT2A (0.53) | RAB9AKMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL16198288 | 0.76 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL8775394 | 0.75 | RAB9A (1.00) | RAB9AKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL8775882 | 0.75 | RAB9A (1.00) | RAB9AKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL7296206 | 0.74 | MAOB (0.57) | RAB9AKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL7296217 | 0.74 | MAOB (0.57) | RAB9AKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL10971774 | 0.72 | ALDH1A1 (0.71) | RAB9AKMT2AALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150463-A1 | Substituted 4.5-dihydro-6-vinyl-3(2H)-pyridazinones and 6-vinyl-3(2H)-pyridazinones and process for producing the same | A. Nattermann & Cie. GmbH (DE) | 1985-08-07 | — | — | EP | disclosed |