Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400489 | 0.79 | HSPA5 (0.58) | KDM4EHSD17B10ALDH1A1EPHX1HSPA5 | |
| SCHEMBL7416727 | 0.77 | HSP90AA1 (0.45) | HSPA5CA1CA2CA9LMNA | |
| SCHEMBL13043443 | 0.76 | ALDH1A1 (0.50) | KDM4EHSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL9031190 | 0.74 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL29822237 | 0.73 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1EPHX1CA1 | |
| SCHEMBL4311940 | 0.73 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1EPHX1CA1 | |
| SCHEMBL2388970 | 0.73 | EPHX1 (0.70) | KDM4EHSD17B10ALDH1A1EPHX1LMNA | |
| SCHEMBL10899301 | 0.73 | CA1 (0.41) | KDM4EHSD17B10ALDH1A1HSPA5CA1 | |
| SCHEMBL3782005 | 0.71 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1EPHX1CA1 | |
| SCHEMBL9332922 | 0.70 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1EPHX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140271-A2 | Iodoacetamides | BAYER AG (DE) | 1985-05-08 | — | — | EP | disclosed |