Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814156 | 0.85 | CA1 (0.44) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL11052280 | 0.75 | THRB (0.52) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL11149691 | 0.74 | HSD17B10 (0.45) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL9814173 | 0.73 | SLC9A1 (0.44) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL14135427 | 0.73 | ALDH1A1 (0.42) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL11016442 | 0.73 | KDM4E (0.45) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL29904715 | 0.72 | HDAC1 (0.49) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL8610558 | 0.72 | CA1 (0.47) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL1143315 | 0.72 | HDAC1 (0.49) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL8423555 | 0.71 | HDAC1 (0.46) | CA1CA2CA9ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048693-B1 | DISAZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | disclosed |