SCHEMBL11017293

SCHEMBL11017293

CCCCC(C(=O)O)C(C)(C(O)=S)c1nc2ccccc2o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 2/20 0.40
HSD17B10 Q99714 2/20 0.40
F2 P00734 1/20 0.40
LMNA P02545 1/20 0.40
MIF P14174 1/20 0.40
FAAH O00519 2/20 0.39
TP53 P04637 2/20 0.39
CES1 P23141 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSP90AA1 P07900 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
PPARG P37231 3/20 0.38
PPARA Q07869 3/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017291 0.91 ALDH1A1 (0.37) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11016755 0.81 FAAH (0.41) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11018445 0.81 FAAH (0.41) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11020373 0.77 RAB9A (0.38) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11018502 0.76 ALDH1A1 (0.47) ALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL11022372 0.74 ALDH1A1 (0.38) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11016752 0.74 FAAH (0.38) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11018442 0.74 FAAH (0.38) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11022370 0.72 ALDH1A1 (0.34) KMT2AALDH1A1MAPTHSD17B10F2
SCHEMBL11020692 0.72 RAB9A (0.40) KMT2AALDH1A1MAPTHSD17B10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed