SCHEMBL11016752

SCHEMBL11016752

CCCCCCCCCCCCCCCCCCC(C(O)=S)C(CCCCCCCCCCCCCCCCCC)(C(O)=S)c1nc2ccccc2o1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CES1 P23141 1/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PPARG P37231 5/20 0.36
PPARA Q07869 5/20 0.36
PPARD Q03181 3/20 0.36
F2 P00734 1/20 0.34
LMNA P02545 1/20 0.34
MIF P14174 1/20 0.34
HSF1 Q00613 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11018442 1.00 FAAH (0.38) FAAHALDH1A1MAPTKMT2AHSD17B10
SCHEMBL11018445 0.92 FAAH (0.41) FAAHALDH1A1MAPTKMT2AHSD17B10
SCHEMBL11016755 0.92 FAAH (0.41) FAAHALDH1A1MAPTKMT2AHSD17B10
SCHEMBL11017291 0.80 ALDH1A1 (0.37) FAAHALDH1A1MAPTKMT2AHSD17B10
SCHEMBL11020371 0.78 RAB9A (0.35) ALDH1A1MAPTKMT2ATP53NPSR1
SCHEMBL11018983 0.78 ALDH1A1 (0.33) FAAHALDH1A1MAPTKMT2AHSD17B10
SCHEMBL11019368 0.77 NPC1 (0.39) ALDH1A1NPSR1
SCHEMBL11018472 0.77 NPC1 (0.39) ALDH1A1NPSR1
SCHEMBL9811004 0.77 L3MBTL1 (0.37) ALDH1A1MAPTKMT2ALMNA
SCHEMBL9811129 0.77 L3MBTL1 (0.37) ALDH1A1MAPTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161219-A2 Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed