Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018454 | 1.00 | PDE3B (0.34) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL11020025 | 0.81 | PDE3B (0.50) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11020022 | 0.81 | PDE3B (0.50) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10725018 | 0.72 | ALDH1A1 (0.53) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL11020513 | 0.70 | PDE3B (0.49) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL11020516 | 0.70 | PDE3B (0.49) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL16692753 | 0.65 | CYP3A4 (0.44) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL7284849 | 0.63 | LMNA (0.44) | — | |
| SCHEMBL2050580 | 0.63 | CYP3A4 (0.42) | PDE3BPDE3AMGAMGAASI | |
| SCHEMBL10764950 | 0.62 | PTGS1 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150463-A1 | Substituted 4.5-dihydro-6-vinyl-3(2H)-pyridazinones and 6-vinyl-3(2H)-pyridazinones and process for producing the same | A. Nattermann & Cie. GmbH (DE) | 1985-08-07 | — | — | EP | disclosed |